Advocate 25kg

advocate 25kg

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Product Description

Advocate XL Dog For Dogs 25-40kg is for dogs suffering from, or at risk from, mixed parasitic infections: For the treatment and prevention of flea infestation (Ctenocephalides felis), treatment of biting lice (Trichodectes canis), treatment of Angiostrongylus vasorum and treatment of infections with gastrointestinal nematodes (L4 larvae, immature adults and adults of Toxocara canis, Ancylostoma caninum and Uncinaria stenocephala, adults of Toxascaris leonina and Trichuris vulpis). The product can be used as part of treatment strategy for flea allergy dermatitis (FAD).

10 – 16

2.5 – 4

> 40 kg

Appropriate combination of pipettes

What can Advocate be used for?

Flea treatment and prevention

One treatment prevents further flea infestation for 4 weeks. Pre-existing pupae in the environment may continue to emerge for 6 weeks or longer after treatment is initiated depending upon climatic conditions. Therefore, it may be necessary to combine Advocate treatment with treatments aimed at breaking the flea life cycle in the surroundings. This can result in more rapid reductions in the household flea population. Advocate should be administered at monthly intervals when used as part of a treatment strategy for flea allergy dermatitis.

Treatment of biting lice (Trichodectes canis)

A single dose should be administered. A further veterinary examination 30 days after treatment is recommended as some animals may require a second treatment.

Treatment of ear mite infestation (Otodectes cynotis)

A single dose of the product should be administered. Loose debris should be gently removed from the external ear canal at each treatment. A further veterinary examination 30 days after treatment is recommended as some animals may require a second treatment. Do not apply direct to the ear canal.

Treatment of sarcoptic mage (caused by Sarcoptes scabiei var.canis)

A single dose should be administered twice 4 week apart.

Treatment of demodicosis (caused by Demodex canis)

A single dose administered 2 to 4 times at 4 weekly intervals is efficacious against Demodex canis and leads to a marked improvement of clinical signs. As demodicosis is a multi-factorial disease, where possible, it is advisable to also treat any underlying disease appropriately.

Heartworm Prevention

For prevention of heartworm disease, the product must be applied at regular monthly intervals during the time of the year when mosquitoes (the intermediate hosts which carry and transmit heartworm larvae) are present. The product may be administered throughout the year or at least 1 month before the first expected exposure to mosquitoes. The treatment should continue at regular monthly intervals until 1 month after the last exposure to mosquitoes. To establish a treatment routine, it is recommended that the same day or date be used each month. When replacing another heartworm preventative product in a heartworm prevention programme, the first treatment with Advocate must be given within 1 month of the last dose of the former medication.

In non-endemic areas there should be no risk of dogs having heartworm. Therefore they can be treated without special precautions.

Treatment of Angiostrongylus vasorum

A single dose should be administered. A further veterinary examination 30 days after treatment is recommended as some animals may require a second treatment.

Roundworm, hookworm and whipworm treatment

In areas endemic for heartworm, monthly treatment may significantly reduce the risk of re-infection caused by the respective roundworms, hookworms and whipworms. In areas non-endemic for heartworm, the product can be used as part of a seasonal prevention programme against fleas and gastrointestinal nematodes.

Studies have shown that monthly treatment of dogs will prevent infections caused by Uninaria Stenocephala.

Usage / Instructions

Caution before using Advocate Xl Dog 25-40kg:

  • Do not store above 30°C
  • Do not use in puppies under 7 weeks of age.
  • Do

    not use in the case of hypersensitivity to the active substances or to any of the excipients.

  • There is limited experience on the use of the product in sick and debilitated animals, thus the product should only be used based on a risk-benefit assessment for these animals.
  • For dogs, the ‘Advocate Spot-on Solution for dogs’, which contains 10 % imidacloprid and 2.5 % moxidectin, must be used.
  • Use of the product may result in transient pruritus in the animal. On rare occasions greasy fur, erythema and vomiting can occur. These signs disappear without further treatment. The product may, in rare cases cause local hypersensitivity reactions. If the animal licks the application site after treatment, transient neurological signs may be observed infrequently. The product may in very rare cases cause at the application site a sensation resulting in transient behavioural changes such as lethargy, agitation, and inappetence.
  • The product tastes bitter. Salivation may occasionally occur if the animal licks the application site immediately after treatment. This is not a sign of intoxication and disappears within some minutes without treatment. Correct application will minimise licking of the application site.
  • Care should be taken that the contents of the pipette or the applied dose does not come into contact with the eyes or mouth of the recipient and/or other animals. Do not allow recently treated animals to groom each other. When the product is applied in 3 to 4 separate spots in larger dogs, specific care should be taken to prevent the animal licking the application sites.
  • This product contains moxidectin (a macrocyclic lactone), special care should be taken with Collies, Old English Sheepdogs and related breeds or crossbreeds, to correctly administer the product as described above. In particular, oral uptake by the recipient and/or other animals should be prevented.
  • Although the product may be safely administered to dogs infected with adult heartworms, it has no therapeutic effect against adult Dirofilaria immitis. It is therefore recommended that all dogs 6 months of age or more, living in areas endemic for heartworm, should be tested for existing adult heartworm infection before being treated with the product.
  • The safety of the veterinary medicinal product has not been established during pregnancy and lactation. Laboratory studies with either imidacloprid or moxidectin in rats and rabbits have not produced any evidence of teratogenic, foetotoxic or maternotoxic effects. Use only according to the risk-benefit assessment.
  • During treatment with Advocate no other antiparasitic macrocyclic lactone should be administered.
  • No interactions between Advocate and routinely used veterinary medicinal products or medical or surgical procedures have been observed.
  • Avoid contact with skin, eyes or mouth.
  • Do not eat, drink or smoke during application.
  • Wash hands thoroughly after use.
  • After application do not stroke or groom animals until the application site is dry.
  • In case of accidental spillage onto skin, wash off immediately with soap and water.
  • People with a known hypersensitivity to either benzyl alcohol, imidacloprid or moxidectin should administer the product with caution. In very rare cases the product may cause skin sensitisation or transient skin reactions (for example allergy, irritation or tingling).
  • If the product accidentally gets into eyes, they should be thoroughly flushed with water.
  • If skin or eye symptoms persist, or the product is accidentally swallowed, seek medical attention and show the package insert to the physician.
  • Any unused product or waste materials derived from such veterinary medicinal products should be disposed of in accordance with local requirements.
  • Advocate should not be allowed to enter surface waters as it has harmful effects on aquatic organisms: moxidectin is highly toxic to aquatic organisms. Dogs should not be allowed to swim in surface waters for 4 days after treatment.

You should carefully read all product packaging and labels prior to use


Category: Advocate

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